Fine needle aspiration cytology in bone lesions

To assess the efficiency of fine needle aspiration cytology [FNAC] in the diagnosis of bone/esions. This Prospective study was conducted in the orthopedic surgical wards at Al- Zahrawi teaching hospital of the Mosul city over one year period from 2003-2004 Thirty seven patients presented with bone lesions were included in this study. The lesions were provisionaly diagnosed by clinical and radiological methods. The results of the aspirated lesions include 20 malignant lesions, 8 tumour like lesions, 5 benign and potentially malignant lesions and 3 inflammatory lesions. In one aspirate the materials was inadequate. The results were compared with the histopathological diagnosis. FNAC of bone lesion is safe, quick, easy, economical and helpful in planning the correct therapy

Result of bronchoscopic biopsies, bronchial brush wash cytology in diagnosis of bronchogenic carcinoma

The results of a prospective study using bronchoscopic biopsies and bronchial brush, wash cytology in 109 patients evaluated for bronchogenic carcinoma are presented. Among 83 patients with bronchogenic carcinoma, a positive cytological diagnosis was made in 68 patients [81.9%]. The bronchoscopic biopsies were positive in 73 patients [87.9%]. When combined together a correct diagnosis was made in all the cases. No false positive diagnosis was made in 26 patients with nonmalignant lesions. The sensitivity and specificity of cytological examinations was 81.9% and 100% respectively whereas that of bronchoscopic biopsy was 87.9% and 100% respectively. Thus cytological examination represents a useful complementary test to endoscopic biopsies in the diagnosis of bronchogenic carcinoma

role of fine needle aspiration cytology in the diagnosis of breast lesions

Fine needle aspiration cytology [FNAC] was performed on ninety eight patients with breast lesions.There were eighteen patients with Inflammatory lesions, thirty seven patients with benign tumours, and forty three patients with malignant tumours. The sensitivity of the technique was 96%, the specificity was 100% and the overall accuracy 97%. The advantages, limitations and possible complications were discussed

Reduction of experimentally induced endometrial hyperplasia by atenolol

This project was initiated to examine an observation noted in Mosul University Gynaocological Clinic where a hypertensive woman was presented with uterine bleeding due to endometrial hyperplasia. Upon lowering her elevated blood pressure with atenolol, the endometrial bleeding decreased gradually and finally stopped. Varying degrees of endometrial hyperplasia were induced in rats by different doses of estradiol valerated injections for a period of 20 days. When atenolol was administered orally in 4 and 8mg doses for the 2nd half of the treatment period, there was significant reduction in uterine wet weight especially in rats [P < 0.001] dosed with high estrogen and atenolol. There was a reduction also in control rats who received the atenolol alone. The endometria of the estrogen dominated rats were thick, vascular, with active surface epithelium and the glands were lined by columnar epithelium with no vacuoles. In the atenolol treated rats, the endometria were thin, less vascular and glandular linings were flattened epithelium with various degrees of secretory exhaustion or secretory vacuoles depending on the dosage of atenolol used

Surgical pathology of thyroid diseases in the Northern part of Iraq

During the years 1978-1983, 1100 thyroid biopsies were received in the pathology department of Mosul Medical College. Analysis of these biopsies showed: 79.1% colloid goitre [diffuse and nodular], 9.1% adenoma, 4.3% toxic goitre, 4.3% malignant neoplasm, 2.3% Hashimoto's thyroiditis, 0.5% de Quervain's thyroiditis, 0.3% parasitic infestation, 0.1% Reidle's thyroiditis, 0.1% tuberculosis, 0.1% pyogenic infection. The age and sex distributions were presented and some of the aetiological factors and preventive measures were reviewed